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Mechanisms of “kidney governing bones” theory in traditional Chinese medicine

Dahong Ju,Meijie Liu,Hongyan Zhao,Jun Wang

Frontiers of Medicine 2014, Volume 8, Issue 3,   Pages 389-393 doi: 10.1007/s11684-014-0362-y

Abstract: Conclusions can be summarized as follows. (1) Neuroendocrine-immune network (NIN)-osteoclast regulatorypathway OPG-RANKL-RANK is one of the mechanisms of “kidney governing bones.” Although kidney-reinforcing therapy is regarded as one of the holistic regulatory mechanisms

Keywords： kidney governing bones     kidney deficiency     marrow     osteoporosis     neuroendocrine-immune network     osteoclastregulatory pathway    

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Regulatory factors of mesenchymal stem cell migration into injured tissues and their signal transduction

Li LI, Jianxin JIANG

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 33-39 doi: 10.1007/s11684-011-0114-1

Abstract: This review will briefly summarize the regulatory facors and signaling transduction pathways involved

Keywords： mesenchymal stem cells     migration     molecular mechanisms     signaling pathway    

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MicroRNAs and their roles in osteoclast differentiation

Zhuying Xia, Chao Chen, Peng Chen, Hui Xie, Xianghang Luo

Frontiers of Medicine 2011, Volume 5, Issue 4,   Pages 414-419 doi: 10.1007/s11684-011-0168-0

Abstract: proliferation and differentiation, few miRNAs have been reported to play a key role in the regulation of osteoclast

Keywords： miRNA     osteoclast differentiation     antagomirs    

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The regulatory sciences for stem cell-based medicinal products

Bao-Zhu Yuan,Junzhi Wang

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 190-200 doi: 10.1007/s11684-014-0323-5

Abstract: Moreover, some stem cell-based products have been approved for marketing by different national regulatoryexist and need to be urgently addressed, especially in countries where establishment of appropriate regulatoryMore relevantly, the stem cell regulatory sciences need to be established or improved to more effectivelyevaluate quality, safety and efficacy of stem cell products, and for building up the appropriate regulatoryregulations, and the associated challenges, and we then propose some considerations for improving stem cell regulatory

Keywords： cell-based medicinal products (SCMPs)     stem cell therapy (SCT)     safety     effectiveness     standards     guidelines     regulatory    

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Low-temperature caproate production, microbial diversity, and metabolic pathway in xylose anaerobic fermentation

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 3, doi: 10.1007/s11783-023-1637-9

Abstract:

● Converting xylose to caproate under a low temperature of 20 °C by MCF was verified.

Keywords： Xylose fermentation     Caproate     Low temperature     Bifidobacterium     FAB pathway     RBO pathway    

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Zero E-waste: Regulatory impediments and blockchain imperatives

Mengjun Chen, Oladele A. Ogunseitan

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 6, doi: 10.1007/s11783-021-1402-x

Abstract: Increasingly, 3re implementation is restricted by regulatory difficulties, particularly the invocation

Keywords： Blockchain     E-waste     Regulatory Policy     Copyright Laws     Repair-Reuse-Remanufacture     Toxicity    

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Disinfection byproducts in drinking water and regulatory compliance: A critical review

Xiaomao WANG,Yuqin MAO,Shun TANG,Hongwei YANG,Yuefeng F. XIE

Frontiers of Environmental Science & Engineering 2015, Volume 9, Issue 1,   Pages 3-15 doi: 10.1007/s11783-014-0734-1

Abstract: This critical review focuses on the issues associated with DBP regulatory compliance, including methodsPrecursor removal and alternative disinfectants are common practices for DBP regulatory compliance.

Keywords： Disinfection byproducts (DBPs)     drinking water standards     regulatory compliance     alternative disinfection    

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Liver cell therapies: cellular sources and grafting strategies

Frontiers of Medicine 2023, Volume 17, Issue 3,   Pages 432-457 doi: 10.1007/s11684-023-1002-1

Abstract: development of genetic sequencing technologies, research on the liver’s cellular composition and its regulatory

Keywords： liver regeneration     hepatocytes     cholangiocytes     stem cells     organoids     regulatory mechanisms     transplantation    

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FERM domain-containing protein FRMD6 activates the mTOR signaling pathway and promotes lung cancer progression

Frontiers of Medicine 2023, Volume 17, Issue 4,   Pages 714-728 doi: 10.1007/s11684-022-0959-5

Abstract: FRMD6 interacts and colocalizes with mTOR and S6K, which are the key molecules of the mTOR signaling pathwayFurthermore, knocking out FRMD6 inhibits the activation of the mTOR signaling pathway in Frmd6our results show that FRMD6 contributes to lung cancer progression by activating the mTOR signaling pathway

Keywords： FRMD6     lung cancer     mTOR pathway    

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Exploring the methodology and application of clinical pathway in evidence-based Chinese medicine

Sicheng Wang, He Yu, Jianping Liu, Baoyan Liu

Frontiers of Medicine 2011, Volume 5, Issue 2,   Pages 157-162 doi: 10.1007/s11684-011-0128-8

Abstract: At present, clinical pathway has become one of the most important health care reform measures in manyIn this study, the authors introduced basic concepts and explored the application of the clinical pathwaySuch concepts provide examples and experiences, on which the application of clinical pathway in Chinese

Keywords： evidence-based medicine     clinical pathway     methodology     concept     technical difficulty    

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Endogenous tissue factor pathway inhibitor in vascular smooth muscle cells inhibits arterial thrombosis

Jichun Yang, Kaiyue Jin, Jiajun Xiao, Jing Ma, Duan Ma

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 403-409 doi: 10.1007/s11684-017-0522-y

Abstract:

Tissue factor pathway inhibitor (TFPI) is the main inhibitor of tissue factor-mediated coagulationEndothelium-derived TFPI has been reported to play a regulatory role in arterial thrombosis.

Keywords： arterial thrombosis     conditional knockout mice     tissue factor pathway inhibitor     vascular smooth muscle    

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Apigenin alleviates neomycin-induced oxidative damage via the Nrf2 signaling pathway in cochlear hair

Frontiers of Medicine 2022, Volume 16, Issue 4,   Pages 637-650 doi: 10.1007/s11684-021-0864-3

Abstract: Further evidence suggested that the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway

Keywords： apigenin     aminoglycosides     ototoxicity     oxidative stress     Nrf2 signaling pathway    

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Biosynthetic pathway of terpenoid indole alkaloids in Catharanthus roseus

Xiaoxuan Zhu,Xinyi Zeng,Chao Sun,Shilin Chen

Frontiers of Medicine 2014, Volume 8, Issue 3,   Pages 285-293 doi: 10.1007/s11684-014-0350-2

Abstract: Here we review the recent advances in the biosynthetic pathway of terpenoid indole alkaloids (TIAs) inSecologanin is derived from terpenoid (isoprenoid) biosynthetic pathway, while tryptamine is derivedfrom indole biosynthetic pathway.Although many genes and corresponding enzymes have been characterized in this pathway, our knowledgeon the whole TIA biosynthetic pathway still remains largely unknown up to date.

Keywords： Catharanthus roseus     terpenoidindole alkaloids     biosynthetic pathway     vinblastine     vincristine    

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METABOLIC AND TRANSCRIPTOME ANALYSIS REVEALS METABOLITE VARIATION AND FLAVONOID REGULATORY NETWORKS IN

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 2,

Abstract: Here, we focus on the seasonal variation in metabolites of fresh tea shoots and their regulatory mechanismWe focused on the metabolites and key genes in the phenylpropanoid/flavonoid pathway integrated withLevels of most key genes and downstream compounds in the flavonoid pathway were lowest in spring butThe regulatory pathway was explored by constructing a metabolite correlation network and a weighted gene
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Genetic evidence in planar cell polarity signaling pathway in human neural tube defects

Chunquan Cai, Ouyan Shi

Frontiers of Medicine 2014, Volume 8, Issue 1,   Pages 68-78 doi: 10.1007/s11684-014-0308-4

Abstract: The planar cell polarity (PCP) pathway controls the process of convergent extension (CE) during gastrulationThis review summarizes the cumulative results of recent studies on PCP signaling pathway and human NTDs

Keywords： planar cell polarity     neural tube defects     rare mutations    

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Title Author Date Type Operation

Mechanisms of “kidney governing bones” theory in traditional Chinese medicine

Dahong Ju,Meijie Liu,Hongyan Zhao,Jun Wang

Journal Article

Regulatory factors of mesenchymal stem cell migration into injured tissues and their signal transduction

Li LI, Jianxin JIANG

Journal Article

MicroRNAs and their roles in osteoclast differentiation

Zhuying Xia, Chao Chen, Peng Chen, Hui Xie, Xianghang Luo

Journal Article

The regulatory sciences for stem cell-based medicinal products

Bao-Zhu Yuan,Junzhi Wang

Journal Article

Low-temperature caproate production, microbial diversity, and metabolic pathway in xylose anaerobic fermentation

Journal Article

Zero E-waste: Regulatory impediments and blockchain imperatives

Mengjun Chen, Oladele A. Ogunseitan

Journal Article

Disinfection byproducts in drinking water and regulatory compliance: A critical review

Xiaomao WANG,Yuqin MAO,Shun TANG,Hongwei YANG,Yuefeng F. XIE

Journal Article

Liver cell therapies: cellular sources and grafting strategies

Journal Article

FERM domain-containing protein FRMD6 activates the mTOR signaling pathway and promotes lung cancer progression

Journal Article

Exploring the methodology and application of clinical pathway in evidence-based Chinese medicine

Sicheng Wang, He Yu, Jianping Liu, Baoyan Liu

Journal Article

Endogenous tissue factor pathway inhibitor in vascular smooth muscle cells inhibits arterial thrombosis

Jichun Yang, Kaiyue Jin, Jiajun Xiao, Jing Ma, Duan Ma

Journal Article

Apigenin alleviates neomycin-induced oxidative damage via the Nrf2 signaling pathway in cochlear hair

Journal Article

Biosynthetic pathway of terpenoid indole alkaloids in Catharanthus roseus

Xiaoxuan Zhu,Xinyi Zeng,Chao Sun,Shilin Chen

Journal Article

METABOLIC AND TRANSCRIPTOME ANALYSIS REVEALS METABOLITE VARIATION AND FLAVONOID REGULATORY NETWORKS IN

Journal Article

Genetic evidence in planar cell polarity signaling pathway in human neural tube defects

Chunquan Cai, Ouyan Shi

Journal Article